A 15-year-old girl with cystic fibrosis who suffered from an antibiotic-resistant mycobacterium infection has been treated thanks to a "modern" therapeutic approach, phage therapy. Not so modern actually, given that the first experiments date back to the 20s of the last century. But it has only recently been rediscovered and proposed as a valid alternative to antibiotic therapy, especially in the case of resistant bacteria, which are going to become more and more threatening.
Tags: Phage therapy
Intelligent and curious, they love to interact with each other and also with humans. We look more like dolphins than we think ... for better and for worse. They are in fact the only wild species in the world in which a form of Alzheimer has been found, which is similar to the human one. A "natural" model that has raised the interest of scientists, opening a new line of research that helps to combat the disease even in humans.
They are funny to look at, mild and intelligent: that was what we knew about alpacas until 1989. That year, two students discovered by chance one important feature that has long remained unknown. This and other species belonging to camelid family have "miniature" antibodies: smaller than ours and those of most mammals, they can reach even the most difficult targets. Researchers at Boston Children 's Hospital used the so called “nanobodies” to make CAR-T cells better at solid tumors. The study has been published in the journal PNAS.
fight solid tumors
What if response to immunotherapy depends on the microbes inside the intestine? An unusual treatment involving stool transplantation from one patient to another could help those who do not respond to immunotherapy.
Tags: cancer immunotherapy drugs